The Human Herpesviruses (HHV) that Lurks, Waits, and Replicates in You

2015 Virus familyThe virus lurks in the dorsal root ganglion like a terrorist waiting.  Blindsided and forgotten like chickenpox, when it surfaces, the shingles’ rash can look like an alien reptile has left its imprint on your skin and is sometimes referred to as “the devil’s grip.”  The varicella-zoster virus has shadowed the human race for thousands of years causing chickenpox and later in life shingles.  Although researchers are investigating the phenomenon of the herpes virus’s unique ability to replicate itself, as of yet, no known cure exists to oust it from the body, where it dwells in the ganglia and, along with other unwanted guests, in the liver.  The best solution, like dealing with a difficult mother-in-law, is to coexist.

Shingles has increased and is four times as common now as it was sixty years ago.  “It’s increased across all age groups,” says Dr. Barbara Yawn, Chief Scientific Officer at COPD Foundation.

Doctors still don’t know the reason for the increase.  “We’ve done studies, and we just don’t know,” Dr. Yawn says.  “The increase is not due to greater rates of immuno-suppression in the population, not due to lack of boostering, not due to introduction of the chickenpox or varicella vaccine, not due to more doctor’s visits, and not due to access to anti-viral meds.”

The viruses herpes-zoster (VZV) and herpes simplex (HSV), the one that causes cold sores, are neurotropic alpha viruses that live in clusters of nerve cells near the spine called the dorsal root ganglion;  the ganglia is the connection between the nerves coming out of the spinal cord and the peripheral nerves.

There’s some indication VZV thrives on stress.  “I suppose some of it could be due to more widespread stress,” Dr. Yawn says.  “We know that there’s  increased risk of shingles in people who have had adverse life events.”

In fact, Dr. Yawn’s study Risk Factors for Herpes Zoster revealed that female sex, race/ethnicity, family history, and co-morbidities such as asthma, diabetes, and COPD, are risk factors for HZ.

“The herpes zoster and the herpes simplex is a fascinating family of viruses,” says Dr. Yawn.  “They all act in a similar way that they stay dormant for years and don’t cause any symptoms but then can reactivate.”  The viruses hide in the nerve tissues, replicating, surviving, waiting, until the right time, when the immune system is weakened, to spring into action.

Viruses can also sleep in the liver.  Dr. Jeffrey Cohen, Chief of the Medical Virology Section in the Laboratory of Clinical Infectious Diseases at the National Institute of Allergy and Infectious Dieseases, in Bethesda, Md.  says, “The latent VZV along the spine should be the same as VZV that’s sometimes detected in the liver as far as we know.  Hepatitis viruses (A,B,C) infect the liver, and other viruses less commonly infect the liver.  The vertebra of the spine can also be infected by bacteria including tuberculosis, and some fungi can occasionally infect the vertebra and cause abscesses.”

Another member of the family is the cytomegalovirus (CMV), a common virus most people don’t know they have, because it rarely causes symptoms.  Once CMV is in the body, like all herpes, it takes cover in the ganglia. According to the CDC, “Among every 100 adults in the United States, 50–80 are infected with CMV by the time they are 40 years old.”  Yet another relative is the Epstein-Barr virus, that causes infectious mononucleosis or mono as it’s known.  Dr. Cohen says that, “CMV can occasionally infect the spine,” too.

There is not a definitive association of EBV and COVID-19 or zoster and COVID-19.  While there are anecdotes of persons with both infections at or near the same time, this does not prove there is a direct association between them.  The possibility of COVID’s link to herpes is under the microscope. New studies prove that Long Covid variants can live in the body for up to a year and impact the overall immune system. Additional reports with similar features are needed for a true association, experts say.

It’s essential to keep VZV  from reactivating.  “The only way is the shingles’ vaccine,” says Dr. Yawn. “But the vaccine hasn’t been studied in people younger than fifty and so does not have FDA approval.  Shingles and complications like postherpetic neuralgia are less common in people under fifty and many people would need to be vaccinated to prevent one case or one complication.”

How can we supercharge our immune system to fight off the enemy?  “There’s no magic potion,” says Dr. Yawn.  “Some people need to use immuno-suppressive medications for cancer, to prevent rejection of transplanted organs, or to treat some chronic diseases like moderate to severe rheumatoid arthritis.  But for people without these needs, avoiding stress, treating depression, having a healthy, well-balanced diet, activity, and maintaining a normal weight can help.”

Alternative options can strengthen the immune system, too.  Dr. Mary Claire H. Wise, Integrative Family Physician, recommends milk thistle supplements to support the liver and the metabolic detox pathways in the liver.  “When you’re not holding on to toxins, your immune system is able to function better,” says Dr. Wise.  “For herpes viruses, what I have found works best is L-lysine three grams daily, St. John’s Wart 450mg twice a day, and echinacea one gram three times a day to prevent a recurrence.”

Kiki Flynn, the popular YouTube Wellness Guru and Lifestyle Coach, recommends neem supplements, because neem is anti-viral, anti-fungal, and anti-bacterial. Neem mitigates parasites, eczema, and viruses like shingles.  In India, neem trees grow up to fifty feet high, a symbol of health, wealth, and community well-being.  But, advises Kiki, “Check with your doctor and do not take if pregnant or nursing. Take according to label and do not exceed two weeks.”

To detox the liver, Kiki recommends her castor oil deep cleanse pack at Kiki Says.


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Yoga Cures:  Surviving the Here and Now

Can a daily dose of yoga cure a life-threatening illness?

“One of the underlying powers of yoga is a balancing of the autonomic nervous system,” says Dr. David Riley, editor-in-chief, Alternative Therapies in Health and Medicine and clinical associate professor, University of New Mexico Medical School and medical research director, Integrative Medicine. “Yoga with its flowing rhythm of postures and deep breathing can reset the point of balance in the ANS, lower blood pressure, reduce stress and stimulate the overall immune function.” For women living life in today’s world, the responsibility of balancing job and family, the pressure to eat right and look good on top of concern about hereditary illness can trigger an ANS imbalance manifesting itself in a variety of diseases.

The nerve fibers of the ANS and its two divisions, the sympathetic “fight or flight” response and the parasympathetic “rest and digest” response, exist in a constant state of dynamic balance. “The sympathetic nervous system is like the gas pedal of a car and the parasympathetic nervous system is the brake,” says Dr. C. Noel Bairey Merz, medical director of the Preventative and Rehabilitative Cardiac Center, at Cedars-Sinai Medical Center. Too much of one and not enough of the other can create an imbalance. In fact, accurate measurement of heart rate variability through sophisticated ECG devices and computer analysis can be a definitive marker of an ANS imbalance.

“Ten years ago” says Dr. Merz “we didn’t have computers, cell phones and fax machines.  Now, women can shop online, make dinner and catch up on last minute phone calls all at once.”  As Dr. Merz explains yoga can add some of the brake when we’re speeding too fast down life’s fast lane by creating the kind of training effect a runner gets when preparing for a marathon. While biofeedback, meditation and relaxation response training are techniques that, when combined with aerobic exercise, viably reduce stress, yoga offers that elusive all in one cure. Through yoga and focusing inward we can control heart rate, blood pressure, cholesterol and rebalance the ANS to help prevent and even cure illness.

Yoga helps Tammy survive intense reality of heart surgery

At 29, Tammy Moore was diagnosed with a defective congenital aortic valve. All her life she suffered from dizziness and fainting episodes and in the last few years she experienced difficulty breathing and was so exhausted she gained more than fifty pounds.  Tammy was quickly admitted to Cedars Sinai Medical Center for open-heart surgery the very same day she had an appointment with her cardiologist.  Her surgery revealed a unicuspid valve, a dangerous condition that inhibits blood flow.  A normal valve has three parts, leaflets or cusps, but a stenotic valve may have only one cusp making it a unicuspid.

As part of her rehab, Tammy attended the state-of-the-art Cedars-Sinai Integral Yoga Hatha cardiac class based upon Dr. Dean Ornish’s clinical trials and research in reversing heart disease with certified yoga therapist, Nirmala Heriza.  Also director of the Los Angeles Integral Yoga Institute, founded by Sri Swami Satchidananda, Heriza teaches a traditional form of hatha yoga, a system of physical postures over 3,000 years old that includes relaxation and breathing techniques to promote optimal health and reversal of disease.  Heriza is author of Dr. Yoga.   More and more, Heriza sees physical breakdowns in people in the early to mid-thirties related to heart problems, the nervous system and chronic fatigue.  She believes yoga embodies a specific science that rebuilds the central nervous system, stimulates the liver and the kidneys which supports the immune system and reverses the aging process.  In her first one-hour class with Heriza, Tammy’s blood pressure dropped to 134/70 from 146/90.

The first six weeks after open-heart surgery Tammy found herself focused on basic self-care issues like breathing into her Tri-Flo and keeping her seven-inch incision clean.  She was not allowed to push or pull more than ten pounds and soon found herself bored with routine walking.  Now that her physical recovery is progressing Tammy feels yoga helps with the deeper fears and intense reality of having survived open-heart surgery. “There’s so much activity inside the hospital getting ready for a surgery this major. You’re so engrossed in the process — logistics, recovery, visiting friends, doctors, nurses, medication, breathing exercises. I felt like the doctors owned my body instead of me. I slept very little the entire time and I never had time to meditate on the whole experience. All of a sudden I realized how vulnerable and dramatic and serious my condition was. Yoga helps me to be quiet and to accept and process what happened to me.”

Two weeks after her surgery, lying in bed late one night dozing to a movie on cable, Tammy’s eyes flew open with the sudden realization of what had happened to her. “It takes a long time for the mind to catch up with the body,” Tammy says. “Even though you have all these caregivers in the hospital, they’re concerned about your clinical recovery. Nirmala was the first one to ask about my overall well-being. In the hospital, you’re focused on what you can’t do like breathing and walking and in my yoga class I focus on what I can do. Yoga allows the thoughts and issues of what you’ve been through to surface. It helps me to be still and to continue my healing process.”

In Tammy’s first cardiac yoga class with Nirmala, she learned shoulder stand affects the pineal gland, the sound center, of the brain; in Eastern medicine, it is widely held that chanting OM does as well. In the weeks following surgery, Tammy lost 22 pounds and happily discovered Cobra pose and shoulder stand, which stimulates the thyroid gland, increases circulation into the heart and helps with body weight. Head to knee pose stimulates the sympathetic nervous symptom increasing circulation of blood into the coronary arteries helping to reduce plaque and lower cholesterol. Modified shoulder stand brings fresh blood supply to the heart and the cranial viscera. Yoga nidra, the hatha yoga pose known as guided meditation, is comparable to approximately three hours of sleep in its clinical affect on the nervous system. “Combined,” Heriza says, “all these poses have a cumulative rehabilitative affect for patients who have undergone surgery.”

Yogic breathing techniques bring vital energy into the system, revitalize all the primary organs, oxygenate the blood and system and enhance circulation. Breathing stabilizes the central nervous system and as a result reduces stress, critical for a heart patient like Tammy. “When you wake up from heart surgery your chest feels so tight,” Tammy says. “You have to wear an oxygen mask and breathing tubes until you can breathe on your own. The first time I stood up two days after my surgery I almost collapsed while they were untangling all the wires on me.” Her doctors told her the more breathing exercises she performed the quicker her condition would improve. “The day after I began to truly concentrate on my breathing exercises the way my doctor said,” she says. “I felt so much better. It was amazing. I turned the corner.”

Yoga helps Renée survive painful symptoms of anorexia nervosa

Yoga rescued Renée M. who at age 26 was 5”6 and 80 pounds. After five months on and off a Dallas cardiac unit and suffering from anorexia nervosa for almost ten years, she enrolled for inpatient treatment at  Monte Nido Eating Disorders Center in Malibu, CA. “By the time I got to Monte Nido other programs wouldn’t even take me. No one thought I’d ever survive,” Renée admits. “I was dying.”  Peer pressure, feeling like a “nerd,” an alcoholic parent, and feeling as if she’d never be enough formed the beginning of an eating disorder.  Now fully recovered from anorexia, Renée credits yoga as a big part of her journey. “Yoga was an integral part of my full and complete recovery from an illness that nearly cost me my life.”

When Renée was first admitted into treatment her muscles were so atrophied and her joints so stressed she barely had the strength to hold up her frame.  Muscle constriction exacerbated her breathing and asthma.  Physically, her body was so depleted she had little strength for strenuous exercise. But she felt desperate to move her body and basic yoga meditation, deep breathing and simple stretching was the only form of exercise the doctors allowed.  To her surprise, Renée discovered yoga helped to stretch and strengthen her new, developing muscles. “It’s hard for me to explain but I know as I learned to create space for breathing in my body, I also began to create space for myself in the world. Yoga allows me to move, breathe and feel. For the first time I was sitting still with myself and just being inside a body I had long before discarded and disengaged from,” she says.

For Renée, high impact cardio exercise felt too harsh on a body so weathered having run at least three to five miles a day and often farther when she was sick. Yoga gave her a gentle way to acknowledge her body and a pace that could be eased into with simple stretching. Child’s pose, tree pose, pigeon pose and sun salutations, some of her favorites, began to take away the painful, arthritic strain that had developed in her joints from running so hard during the years of her illness, allowing her to breathe in more air with better expansion and capacity. Both Renée’s internist and chiropractor agree yoga was critical to her recovery.  “I went from bed rest years ago to standing beside Hillary Clinton at the National Eating Disorders Coalition,” says Renée, now a successful healthy 32-year-old therapist. “Having come from a near death place to being fully alive is a wonderful thing.”

Cancer diagnosis affects body, mind and spirit

At 26, Elizabeth, a pediatric registered nurse, was diagnosed with breast cancer and underwent a mastectomy on her right breast.  A competitive swimmer since childhood, Elizabeth quickly returned to swimming on her own after surgery. Bald and sick, one year after she completed her chemotherapy and radiation treatment, she joined a master’s swim team. At her first practice Nike happened to be scouting a swimmer for a commercial. Elizabeth scored as one of several featured female athletes and was impressed by the woman practicing yoga in the same commercial. It wasn’t long before Elizabeth checked out a level one yoga class. “I wish I had known about yoga earlier in my illness,” she says. “Yoga teaches you how to relax in the midst of intensity, which is an essential skill for a cancer patient. You have to be able to take hold and let go at the same time.”  Yoga was a different mindset for her and a real departure from competitive swimming.  For Elizabeth, yoga, with its focus on self-awareness, is more about what you get out of it and not about getting every pose. The class she now attends at Yoga Works in Santa Monica, CA teaches relaxing hatha poses beginning with meditation, sun salutations, standing poses and finishing up with a simple savasana.

Last summer Elizabeth had reconstructive surgery, a procedure called superior gluteal free flap breast reconstruction, where the buttock is used as donor tissue to reconstruct the breast.  For the first two weeks she could not lift her right arm more than 45 degrees. Yoga has been beneficial in regaining her sense of motion.  Where swimming came easily to her, yoga offers her a challenge to stretch her shoulder, chest and right arm. One of her favorite poses is apanasana, knee to chest pose, because it stretches the shoulders and arms when you lie on your back with your knees bent.  After being diagnosed with cancer, Elizabeth felt her body had betrayed her. “Yoga engages the body, mind and spirit all of which are affected by a cancer diagnosis,” she says. “I find yoga very therapeutic in this way.”  Over time she has begun to see herself as a survivor and has found renewed faith in her body.  Elizabeth finds yoga helps her to acknowledge, appreciate and respect her body as a gift.

Lisa chooses yoga as an alternative to spinal surgery

In the nineties, actress Lisa Edelstein, well known for her role in “House” underwent a C4-C5 spinal fusion in her neck.  What had been an optional surgery for a herniated disc turned into an emergency when four days before her scheduled fusion she was rear-ended in a car.  In surgery, the doctors took a bone from her hip and put it into her neck. Two years later, Lisa experienced a spasm in her neck that was so painful her hand went numb. She couldn’t lift her head up all the way, turn it to the right or straighten her arm without excruciating pain; her arm was lined with black bruises from constantly massaging it in an effort to try and stop the ever-present pain shooting down from her shoulder. Exhausted, miserable and depressed on painkillers and anti-inflammatory, she cried non-stop. Her doctor told her C5-C6 was now herniated and would need fusion, a second surgery, and that this domino effect would continue because each fusion would put more pressure on the vertebra around it.  Lisa felt that if surgery had been a solution another wouldn’t be necessary. Instead, she turned to Dr. John Sarno’s book  Healing Back Pain and realized his description of the type of person who might experience this kind of back pain — a perfectionist, ambitious, high energy, goal-oriented — fit her. Dr. Sarno’s book prescribed exercise and inward emotional exploration, saying that stress, not a herniated disc, caused such pain.

After reading Dr. Sarno’s life-altering book, Lisa committed herself to a different future than the bleak one her doctor had prescribed.  She gave Bikram yoga a try, a form of yoga where the room is heated to 90–105 degrees, allowing muscles to quickly warm and stretch. She never discussed her decision with her doctor and never went back to him. Although Lisa believes her doctor might have suggested yoga would be a good way to stretch and possibly reduce the number of surgeries she might need, she doesn’t think he could even begin to imagine the extent of the change that has occurred.  In the stressful world of show business, Lisa says her battle was more emotional than physical. “Thanks to a daily yoga practice I handle stress differently in mind and body. Now, I’m so strong physically that what stress I do have can be tolerated to a much greater degree.”

Within months she went from feeling completely disabled to feeling almost one hundred percent. “It was amazing.  I had my life back,” she says.  After rehabilitating in Bikram yoga for nine months, Lisa started Ashtanga, a more strenuous form of yoga, for strength and meditation doing poses she thought she’d never be able to physically manage again. “I feel incredible. I’m much more flexible than I thought mathematically possible. Sure, I get a stiff neck from time to time like anybody, but I have never fallen back into the state I was way back when.  I feel so strong and powerful.  I have arms and shoulders to support me that I never dreamed imaginable. And I have a practice that helps me quiet my mind and keep me from ever having to take life out on myself again.”

How does yoga, available cost-efficient medical therapy that doesn’t concern itself with preexisting condition, help in curing debilitating and even life-threatening illness?  “We know the autonomic nervous system plays a role in all diseases,” says Dr. Riley. “Yoga postures, deep breathing and inward reflection have the power to put the ANS back in balance. Our ANS is a dynamic system that balances our ability to relax with taking action. In today’s fast paced culture, a discipline like yoga can have profound effects on self-healing.”

published in SELF magazine, 2002


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